The new standard in automated patch clamp technology
Fully automated, walk away, patch clamp system
Data quality equivalent to manual patch clamp systems
Voltage and current clamp recordings
Whole-cell, cell attached and perforated patch protocols
works with cell lines, stem cells, and primary cells
Only automated patch clamp system using galss pipettes analogous to manual patch clamp
- Simple translation of manual patch clamp protocols to automation
G§Ù seal resistances with physiologically relevant buffers
- No need for seal enhancing buffers that can effect data quality
Fiexible perfusion system
- Continuous compound perfusion ideal for "show on" voltage gated ion channels
- Ultra-fast compound wash-in (<4ms) perfect for fast desensitising ligand gated ion channels
Two cells only in the perfusion chamber during recording
- No drug sinks
- Minimal compound usage
- Unmatched accuracy of pharmacological data
All new system housing with integrated temperature control
Comprehensive "in-assay" biophysical quality checks ensure only the highest quality data is generated
Scalabel thourghput
GLP compliant
| Seal Resistance | >1 G§Ù |
|---|---|
| Whole-cell Resistance | >1 G§Ù |
| Pipette Resistance (standard chips) | 4 M§Ù and 8 M§Ù *) |
| Perfusion Chamber Volume | 100 nl |
| Cell Consumption | ~150 cells per seal |
| Continuous Perfusion Mode Compound Consumption | <10 §¡ per minute |
| Minimum Compound Application Volume | ~1 §¡ |
| Perfusion Duration | >30 minutes |
| Compound Wash-In Speed | <4 ms |
| Compound Wash-Out Speed | <10 ms |
| Whole Cell Stability | >40 minutes |
| Success Rate-Complete Assay | up to 99% |
| Throughput per hour | up to 4x6 point dose response curves |