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CytoPatch2
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CytoPatch2

The new standard in automated patch clamp technology

Fully automated, walk away, patch clamp system

Data quality equivalent to manual patch clamp systems

Voltage and current clamp recordings

Whole-cell, cell attached and perforated patch protocols

works with cell lines, stem cells, and primary cells

Only automated patch clamp system using galss pipettes analogous to manual patch clamp

- Simple translation of manual patch clamp protocols to automation

G§Ù seal resistances with physiologically relevant buffers

- No need for seal enhancing buffers that can effect data quality

Fiexible perfusion system

- Continuous compound perfusion ideal for "show on" voltage gated ion channels
- Ultra-fast compound wash-in (<4ms) perfect for fast desensitising ligand gated ion channels

Two cells only in the perfusion chamber during recording

- No drug sinks
- Minimal compound usage
- Unmatched accuracy of pharmacological data

All new system housing with integrated temperature control

Comprehensive "in-assay" biophysical quality checks ensure only the highest quality data is generated

Scalabel thourghput

GLP compliant

Seal Resistance >1 G§Ù
Whole-cell Resistance >1 G§Ù
Pipette Resistance (standard chips) 4 M§Ù and 8 M§Ù *)
Perfusion Chamber Volume 100 nl
Cell Consumption ~150 cells per seal
Continuous Perfusion Mode Compound Consumption <10 §¡ per minute
Minimum Compound Application Volume ~1 §¡
Perfusion Duration >30 minutes
Compound Wash-In Speed <4 ms
Compound Wash-Out Speed <10 ms
Whole Cell Stability >40 minutes
Success Rate-Complete Assay up to 99%
Throughput per hour up to 4x6 point dose response curves
*) custom chips available on request

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